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1

Cell cycle, CDKs and cancer: a changing paradigm

Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Reviews Cancer

Year:

2009

Language:

english

File:

PDF, 1.08 MB

english, 2009

2

The Trk family of neurotrophin receptors

Mariano Barbacid

Journal:

Developmental Neurobiology

Year:

1994

Language:

english

File:

PDF, 1.83 MB

english, 1994

3

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

Reddy, E. Premkumar, Reynolds, Roberta K., Santos, Eugenio, Barbacid, Mariano

Journal:

Year:

1982

File:

PDF, 501 KB

1982

4

Timeline: RAS oncogenes: the first 30 years

Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Reviews Cancer

Year:

2003

Language:

english

File:

PDF, 921 KB

english, 2003

5

Mutagens, oncogenes and cancer

Mariano Barbacid

Journal:

Trends in Genetics

Year:

1986

Language:

english

File:

PDF, 747 KB

english, 1986

6

ras Genes

Journal:

Annual Review of Biochemistry

Year:

1987

Language:

english

File:

PDF, 1.43 MB

english, 1987

7

L’induction d’adénocarcinomes pancréatiques par un oncogène KrasG12D endogène est dépendante de la période d’activation de cet oncogène

Dubus, P., Canamero, M., Perez, L., Jimenez, A., Barbacid, M., Guerra, C.

Journal:

Annales de Pathologie

Year:

2006

Language:

french

File:

PDF, 134 KB

french, 2006

8

Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against authochthonous melanomas in the skin

Julia Steitz, Stefanie Büchs, Damia Tormo, Aleix Ferrer, Jörg Wenzel, Christoph Huber, Thomas Wölfel, Mariano Barbacid, Marcos Malumbres, Thomas Tüting

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 485 KB

english, 2006

9

UICC study group on basic and clinical cancer research: Growth factors, receptors and oncogenes. Meeting held at Woods Hole, MA, USA, September 27–30, 1987

Max M. Burger, Mariano Barbacid, Charles D. Stiles

Journal:

International Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 505 KB

english, 1988

10

Transforming genes in human tumors

Simonetta Pulciani, Eugenio Santos, Anne V. Lauver, Linda K. Long, Mariano Barbacid

Journal:

Journal of Cellular Biochemistry

Year:

1982

Language:

english

File:

PDF, 654 KB

english, 1982

11

Using cells devoid of RAS proteins as tools for drug discovery

Jelena Urosevic, Eleanor Y.M. Sum, Victoria Moneo, Matthias Drosten, Alma Dhawahir, Mercedes Becerra, Amancio Carnero, Mariano Barbacid

Journal:

Molecular Carcinogenesis

Year:

2009

Language:

english

File:

PDF, 185 KB

english, 2009

12

Quantitative Assay for Cell Invasion Using the Fluorogenic Substrate 2′,7′-Bis(2-carboxyethyl)-5 (and -6)-carboxyfluorescein Acetoxymethylester

Teresa Garrido, Hans H. Riese, Ana R. Quesada, M.Mar Barbacid, Miguel Aracil

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 67 KB

english, 1996

13

Preparation of pure [3H]anisomycin by tritium exchange labeling

Mariano Barbacid, David Vazquez

Journal:

Analytical Biochemistry

Year:

1973

Language:

english

File:

PDF, 566 KB

english, 1973

14

Corneal innervation and sensitivity to noxious stimuli in trkA knockout mice

Fernando De Castro, Inmaculada Silos-Santiago, Mikel López De Armentia, Mariano Barbacid, Carlos Belmonte

Journal:

European Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 338 KB

english, 1998

15

The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma

Carles Martínez-Romero, Ilse Rooman, Anouchka Skoudy, Carmen Guerra, Xavier Molero, Ana González, Mar Iglesias, Tania Lobato, Almudena Bosch, Mariano Barbacid, Francisco X Real, Inmaculada Hernández-M

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 534 KB

english, 2009

16

Cdk6-Dependent Regulation of G1 Length Controls Adult Neurogenesis

Pierre Beukelaers, Renaud Vandenbosch, Nicolas Caron, Laurent Nguyen, Shibeshih Belachew, Gustave Moonen, Hiroaki Kiyokawa, Mariano Barbacid, David Santamaria, Brigitte Malgrange

Journal:

Year:

2011

Language:

english

File:

PDF, 4.33 MB

english, 2011

17

The human VAV proto-oncogene maps to chromosome region 19p12→19p13.2

Cecile Martinerie, Linda A. Cannizzaro, Carlo M. Croce, Kay Huebner, Shulamit Katzav, Mariano Barbacid

Journal:

Year:

1990

Language:

english

File:

PDF, 576 KB

english, 1990

18

Activation of a type C virus particle in cells from the inbred mouse strain 129/J: Antigenic relationship with the horizontally transmitted type C viruses of primates

U. R. Rapp, M. Barbacid

Journal:

Archives of Virology

Year:

1983

Language:

english

File:

PDF, 607 KB

english, 1983

19

La necesidad de un Pacto de Estado por la Ciencia en España

Jesús Ávila, Miguel Beato, Joan J. Guinovart, José López Barneo, Ginés Morata, Vicente Rubio, Mariano Barbacid, Félix Goñi, Carlos Martínez Alonso, Federico Mayor Menéndez, Margarita Salas

Journal:

Clinical and Translational Oncology

Year:

2004

File:

PDF, 90 KB

2004

20

Effects of dietary fatty acids on the proliferation, adhesion and metastatic potential of breast cancer cells: an experimental review

Javier Abel Menéndez, María del Mar Barbacid, Sagrario Montero, Santiago Ropero, Eduard Escrich, Hernán Cortés-Funes, Ramón Colomer

Journal:

Clinical and Translational Oncology

Year:

2002

File:

PDF, 122 KB

2002

21

Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes

N. Marzo, C. Mora, M. E. Fabregat, J. Martín, E. F. Usac, C. Franco, M. Barbacid, R. Gomis

Journal:

Year:

2004

Language:

english

File:

PDF, 269 KB

english, 2004

22

Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system

Jonas Frisén, Mariano Barbacid

Journal:

Cell and Tissue Research

Year:

1997

Language:

english

File:

PDF, 274 KB

english, 1997

23

Severe Sensory Deficits but Normal CNS Development in Newborn Mice Lacking TrkB and TrkC Tyrosine Protein Kinase Receptors

Inmaculada Silos-Santiago, Anne M. Fagan, Melinda Garber, Bernd Fritzsch, Mariano Barbacid

Journal:

European Journal of Neuroscience

Year:

1997

Language:

english

File:

PDF, 5.63 MB

english, 1997

24

Nerve Dependency of Developing and Mature Sensory Receptor Cells

BERND FRITZSCH, MARIANO BARBACID, INMACULADA SILOS-SANTIAGO

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 3.95 MB

1998

25

gag Gene of mammalian type-C RNA tumour viruses

Barbacid, Mariano, Stephenson, John R., Aaronson, Stuart A.

Journal:

Year:

1976

File:

PDF, 670 KB

1976

26

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

Santos, Eugenio, Tronick, Steven R., Aaronson, Stuart A., Pulciani, Simonetta, Barbacid, Mariano

Journal:

Year:

1982

File:

PDF, 783 KB

1982

27

Oncogenes in solid human tumours

Pulciani, Simonetta, Santos, Eugenio, Lauver, Anne V., Long, Linda K., Aaronson, Stuart A., Barbacid, Mariano

Journal:

Year:

1982

File:

PDF, 555 KB

1982

28

Localization of the normal allele of T24 human bladder carcinoma oncogene to chromosome 11

McBride, O. Wesley, Swan, David C., Santos, Eugenio, Barbacid, Mariano, Tronick, Steven R., Aaronson, Stuart A.

Journal:

Year:

1982

File:

PDF, 280 KB

1982

29

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations

Sukumar, Saraswati, Notario, Vicente, Martin-Zanca, Dionisio, Barbacid, Mariano

Journal:

Year:

1983

File:

PDF, 633 KB

1983

30

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

Zarbl, Helmut, Sukumar, Saraswati, Arthur, Anne V., Martin-Zanca, Dionisio, Barbacid, Mariano

Journal:

Year:

1985

File:

PDF, 963 KB

1985

31

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

Martin-Zanca, Dionisio, Hughes, Stephen H., Barbacid, Mariano

Journal:

Year:

1986

File:

PDF, 784 KB

1986

32

MILESTONES IN CELL DIVISION TO CYCLE OR NOT TO CYCLE: A CRITICAL DECISION IN CANCER

Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Reviews Cancer

Year:

2001

Language:

english

File:

PDF, 703 KB

english, 2001

33

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

Bustelo, Xosé R., Ledbetter, Jeffrey A., Barbacid, Mariano

Journal:

Year:

1992

File:

PDF, 677 KB

1992

34

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

Klein, Rüdiger, Silos-Santiago, Inmaculada, Smeyne, Richard J., Lira, Sergio A., Brambilla, Riccardo, Bryant, Sherri, Zhang, Li, Snider, William D., Barbacid, Mariano

Journal:

Year:

1994

File:

PDF, 465 KB

1994

35

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

Smeyne, Richard J., Klein, Rüdiger, Schnapp, Andreas, Long, Linda K., Bryant, Sherri, Lewin, Anne, Lira, Sergio A., Barbacid, Mariano

Journal:

Year:

1994

File:

PDF, 615 KB

1994

36

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes

Fischer, Klaus-Dieter, Zmuidzinas, Antanina, Gardner, Sandra, Barbacid, Mariano, Bernstein, Alan, Guidos, Cynthia

Journal:

Year:

1995

File:

PDF, 464 KB

1995

37

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

Sánchez, Marina P., Silos-Santiago, Inmaculada, Frisén, Jonas, He, Bin, Lira, Sergio A., Barbacid, Mariano

Journal:

Year:

1996

File:

PDF, 1.44 MB

1996

38

Tumour biology: Senescence in premalignant tumours

Collado, Manuel, Gil, Jesús, Efeyan, Alejo, Guerra, Carmen, Schuhmacher, Alberto J., Barradas, Marta, Benguría, Alberto, Zaballos, Angel, Flores, Juana M., Barbacid, Mariano

Journal:

Year:

2005

Language:

english

File:

PDF, 303 KB

english, 2005

39

10.1038/8751

Reddy, E. Premkumar, Barbacid, Mariano, Rane, Sushil G., Dubus, Pierre, Mettus, Richard V., Galbreath, Elizabeth J., Boden, Guenther

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 1.49 MB

english, 1999

40

10.1038/87522

Reddy, E. Premkumar, Barbacid, Mariano, Rane, Sushil G., Dubus, Pierre, Mettus, Richard V., Galbreath, Elizabeth J., Boden, Guenther

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 29 KB

english, 2001

41

10.1038/88756

Tedford, Kerry, Nitschke, Lars, Girkontaite, Irute, Charlesworth, Amanda, Chan, Gordon, Sakk, Vadim, Barbacid, Mariano, Fischer, Klaus-Dieter

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 1.05 MB

english, 2001

42

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

Drosten, Matthias, Dhawahir, Alma, Sum, Eleanor Y M, Urosevic, Jelena, Lechuga, Carmen G, Esteban, Luis M, Castellano, Esther, Guerra, Carmen, Santos, Eugenio, Barbacid, Mariano

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 2.37 MB

english, 2010

43

Cdk1 is sufficient to drive the mammalian cell cycle

Santamaría, David, Barrière, Cédric, Cerqueira, Antonio, Hunt, Sarah, Tardy, Claudine, Newton, Kathryn, Cáceres, Javier F., Dubus, Pierre, Malumbres, Marcos, Barbacid, Mariano

Journal:

Year:

2007

Language:

english

File:

PDF, 699 KB

english, 2007

44

The European dimension for the mouse genome mutagenesis program

Auwerx, Johan, Avner, Phil, Baldock, Richard, Ballabio, Andrea, Balling, Rudi, Barbacid, Mariano, Berns, Anton, Bradley, Allan, Brown, Steve, Carmeliet, Peter

Journal:

Nature Genetics

Year:

2004

Language:

english

File:

PDF, 97 KB

english, 2004

45

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

Ortega, Sagrario, Prieto, Ignacio, Odajima, Junko, Martín, Alberto, Dubus, Pierre, Sotillo, Rocio, Barbero, Jose Luis, Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 3.00 MB

english, 2003

46

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation

Ventura, Juan José, Tenbaum, Stephan, Perdiguero, Eusebio, Huth, Marion, Guerra, Carmen, Barbacid, Mariano, Pasparakis, Manolis, Nebreda, Angel R

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 563 KB

english, 2007

47

RAS oncogenes: The first 30 years

Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Reviews Cancer

Year:

2003

Language:

english

File:

PDF, 39 KB

english, 2003

48

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS

Lauth, Matthias, Bergström, Åsa, Shimokawa, Takashi, Tostar, Ulrica, Jin, Qianren, Fendrich, Volker, Guerra, Carmen, Barbacid, Mariano, Toftgård, Rune

Journal:

Nature Structural and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 753 KB

english, 2010

49

A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70

Rosa, Jose Luis, Barbacid, Mariano

Journal:

Year:

1997

Language:

english

File:

PDF, 322 KB

english, 1997

50

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation

Bustelo, Xosé R, Crespo, Piero, López-Barahona, Mónica, Gutkind, J Silvio, Barbacid, Mariano

Journal:

Year:

1997

Language:

english

File:

PDF, 548 KB

english, 1997

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